Outline
Collagen solution for tissue culturing is a highly purified collagen solution manufactured in our advanced technology with excellent quality control.
Advantages
- All products are sterilized. The used collagen are extracted from bovine dermis, solubilized and purified by our original methods.
- Acidic solutions, I-PC and I-AC, form fibrils when being neutralized at 37°C.
Functional expression of cells cultured with Koken Collagen
Cell cultures with Koken collagen solutions can express cellular functions like in vivo cells. Collagen not only plays the role of physical scaffold for the proliferating cells, but also enhances cell adhesion, proliferation and function. Collagen creates a natural extracellular environment that is important for cell communication and layer formation. The synthesizing capability of albumin, a functions shared among hepatocytes, is maintained at a high level when cultured on plates coated with collagen solution. When skin fibroblasts are cultured three-dimensionally on collagen gel , the whole collagen contracts from the contractility of the cells producing a dermis model that closely resembles the structure of live dermis.
Types of Collagen solutions for tissue culture
| Type of collagen | pH | Concentrations | ||
|---|---|---|---|---|
| Acidic solution | I-PC | Bovine dermis pepsin-solubilized type I(Atelocollagen) collagen solution |
3.0 | 0.3%and0.5%solutions are available |
| I-AC | Bovine dermis acid-solubilized type I collagen solution |
| Product code | Storage | Product name | Package |
|---|---|---|---|
| IPC-30 | 4°C | Acidic collagen solution for tissue culturing, I-PC, pH 3.0, concentration: 0.3 %, Sterile |
50 ml |
| IPC-50 | 4°C | Acidic collagen solution for tissue culturing, I-PC, pH 3.0, concentration: 0.5 %, Sterile |
50 ml |
| IAC-30 | 4°C | Acidic collagen solution for tissue culturing, I-AC, pH 3.0, concentration: 0.3 %, Sterile |
50 ml |
| IAC-50 | 4°C | Acidic collagen solution for tissue culturing, I-AC, pH 3.0, concentration: 0.5 %, Sterile |
50 ml |
